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pubmed-article:21251041pubmed:abstractTextDermatofibrosarcoma protuberans (DFSP) was recently proposed to originate from a nestin-positive stem cell. In postnatal skin, nestin and another embryonic stem cell marker, SOX2, display a similar expression pattern with immunoreactivity in the hair follicle papilla and scattered cells of the perifollicular connective tissue sheath. The distribution pattern differs only in early embryogenesis, when nestin but not SOX2 is also expressed throughout the entire interfollicular dermis. We speculated that DFSP would not only be nestin-positive but also SOX2-positive.lld:pubmed
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pubmed-article:21251041pubmed:copyrightInfoCopyright © 2011 John Wiley & Sons A/S.lld:pubmed
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pubmed-article:21251041pubmed:articleTitleExpression of embryonic stem cell markers SOX2 and nestin in dermatofibrosarcoma protuberans and dermatofibroma.lld:pubmed
pubmed-article:21251041pubmed:affiliationDepartment of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA. klaus.sellheyer@gmail.comlld:pubmed
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