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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-5-2
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pubmed:abstractText |
Epidemiologic studies report an association between pneumonia and urban particulate matter (PM) less than 10 microns (?m) in aerodynamic diameter (PM(10)). Streptococcus pneumoniae is a common cause of bacterial pneumonia worldwide. To date, the mechanism whereby urban PM enhances vulnerability to S pneumoniae infection is unclear. Adhesion of S pneumoniae to host cells is a prerequisite for infection. Host-expressed proteins, including the receptor for platelet-activating factor (PAFR), are co-opted by S pneumoniae to adhere to lower airway epithelial cells.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1097-6825
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1236-42.e2
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pubmed:dateRevised |
2011-11-4
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pubmed:meshHeading |
pubmed-meshheading:21247619-Bacterial Adhesion,
pubmed-meshheading:21247619-Cell Line,
pubmed-meshheading:21247619-Epithelial Cells,
pubmed-meshheading:21247619-Ghana,
pubmed-meshheading:21247619-Great Britain,
pubmed-meshheading:21247619-Humans,
pubmed-meshheading:21247619-Oxidative Stress,
pubmed-meshheading:21247619-Particulate Matter,
pubmed-meshheading:21247619-Platelet Activating Factor,
pubmed-meshheading:21247619-Platelet Membrane Glycoproteins,
pubmed-meshheading:21247619-RNA, Messenger,
pubmed-meshheading:21247619-Receptors, G-Protein-Coupled,
pubmed-meshheading:21247619-Respiratory System,
pubmed-meshheading:21247619-Streptococcus pneumoniae
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pubmed:year |
2011
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pubmed:articleTitle |
Adhesion of Streptococcus pneumoniae to human airway epithelial cells exposed to urban particulate matter.
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pubmed:affiliation |
Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, Queen Mary University London, London, United Kingdom.
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pubmed:publicationType |
Journal Article
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