|
rdf:type |
|
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lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0005516,
umls-concept:C0007133,
umls-concept:C0021083,
umls-concept:C0042149,
umls-concept:C0086418,
umls-concept:C0205250,
umls-concept:C0245557,
umls-concept:C0332324,
umls-concept:C0440743,
umls-concept:C1514559
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|
pubmed:issue |
14
|
|
pubmed:dateCreated |
2011-7-1
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|
pubmed:abstractText |
Uterine serous papillary carcinoma (USPC) was an aggressive and chemotherapy resistant variant of endometrial cancer. The authors evaluated the expression of human trophoblast-cell-surface-marker (Trop-2) and the potential of hRS7, a humanized anti-Trop-2 monoclonal antibody, as a novel therapeutic strategy against USPC.
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pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
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|
pubmed:issn |
1097-0142
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|
pubmed:author |
|
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pubmed:copyrightInfo |
Copyright © 2011 American Cancer Society.
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pubmed:issnType |
Electronic
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pubmed:day |
15
|
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pubmed:volume |
117
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
3163-72
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:21246534-Antibodies, Monoclonal,
pubmed-meshheading:21246534-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:21246534-Antigens, Neoplasm,
pubmed-meshheading:21246534-Carcinoma, Papillary,
pubmed-meshheading:21246534-Cell Adhesion Molecules,
pubmed-meshheading:21246534-Cell Line, Tumor,
pubmed-meshheading:21246534-Female,
pubmed-meshheading:21246534-Humans,
pubmed-meshheading:21246534-Interleukin-2,
pubmed-meshheading:21246534-Uterine Neoplasms
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|
pubmed:year |
2011
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|
pubmed:articleTitle |
Uterine serous papillary carcinomas overexpress human trophoblast-cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-Trop-2 monoclonal antibody.
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|
pubmed:affiliation |
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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