Source:http://linkedlifedata.com/resource/pubmed/id/21246106
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
2011-2-8
|
pubmed:abstractText |
Two complementary formats for kinase inhibitor screening are presented in which peptide-modified gold nanoparticles are enzymatically phosphorylated and rapidly aggregate on a surface or in solution by action of phosphospecific antibodies. The simple and rapid colourimetric response of the assays makes them an attractive approach for drug-screening applications.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1364-548X
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
28
|
pubmed:volume |
47
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2249-51
|
pubmed:meshHeading |
pubmed-meshheading:21246106-Antibodies,
pubmed-meshheading:21246106-Electrochemical Techniques,
pubmed-meshheading:21246106-Gold,
pubmed-meshheading:21246106-Metal Nanoparticles,
pubmed-meshheading:21246106-Phosphopeptides,
pubmed-meshheading:21246106-Phosphorylation,
pubmed-meshheading:21246106-Protein Kinase Inhibitors
|
pubmed:year |
2011
|
pubmed:articleTitle |
Single-step kinase inhibitor screening using a peptide-modified gold nanoparticle platform.
|
pubmed:affiliation |
Imperial College London, Department of Materials and Institute for Biomedical Engineering, Prince Consort Road, London, SW7 2AZ, UK.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|