Linked Life Data

21241061

Source:http://linkedlifedata.com/resource/pubmed/id/21241061

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-2-9
pubmed:abstractText
We employ simple geometrical rules to design a set of nanotopographies able to interfere with focal adhesion establishment during neuronal differentiation. Exploiting nanoimprint lithography techniques on cyclic-olefin-copolymer films, we demonstrate that by varying a single topographical parameter the orientation and maturation of focal adhesions can be finely modulated yielding independent control over the final number and the outgrowth direction of neurites. Taken together, this report provides a novel and promising approach to the rational design of biocompatible textured substrates for tissue engineering applications.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1530-6992
pubmed:author
pubmed:issnType
Electronic
pubmed:day
9
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
505-11
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Nanotopographic control of neuronal polarity.
pubmed:affiliation
NEST, Istituto Nanoscienze-CNR and Scuola Normale Superiore, Pisa, Italy. aferrari@ethz.ch
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't