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rdf:type |
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lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0006935,
umls-concept:C0017262,
umls-concept:C0185117,
umls-concept:C0205103,
umls-concept:C0392756,
umls-concept:C0441889,
umls-concept:C0813622,
umls-concept:C1140999,
umls-concept:C1420801,
umls-concept:C1880497,
umls-concept:C1996904,
umls-concept:C1999216,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
2011-1-17
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pubmed:abstractText |
The exact mechanism of capsular contracture (CC) is still unknown. The covalent modification of hyaluronan (HA) with the heavy chains (HC) of inter-?-inhibitor (I?I) has been identified as an important pathway in inflammation and tissue remodeling, where HC·HA formation is catalyzed by TSG-6 (the protein product of tumor necrosis factor stimulated gene-6).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1527-330X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-55
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pubmed:dateRevised |
2011-9-12
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pubmed:meshHeading |
pubmed-meshheading:21239672-Adult,
pubmed-meshheading:21239672-Alpha-Globulins,
pubmed-meshheading:21239672-Breast Implants,
pubmed-meshheading:21239672-Cell Adhesion Molecules,
pubmed-meshheading:21239672-Female,
pubmed-meshheading:21239672-Fluorescent Antibody Technique,
pubmed-meshheading:21239672-Gene Expression Regulation,
pubmed-meshheading:21239672-Humans,
pubmed-meshheading:21239672-Hyaluronic Acid,
pubmed-meshheading:21239672-Implant Capsular Contracture,
pubmed-meshheading:21239672-Middle Aged,
pubmed-meshheading:21239672-Polymerase Chain Reaction,
pubmed-meshheading:21239672-Severity of Illness Index
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pubmed:year |
2011
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pubmed:articleTitle |
Hyaluronan, TSG-6, and inter-?-inhibitor in periprosthetic breast capsules: reduced levels of free hyaluronan and TSG-6 expression in contracted capsules.
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pubmed:affiliation |
National Institute for Health Research and Plastic & Reconstructive Surgery Research, University of Manchester, 131 Princess Street, Manchester, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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