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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1991-1-22
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pubmed:databankReference | |
pubmed:abstractText |
The nucleotide (nt) sequences of the genes encoding argininosuccinate synthetase from Escherichia coli K-12 (argG) and Saccharomyces cerevisiae (ARG1) were determined. The deduced amino-acid sequences were compared to each other and to their counterparts in two methanogens and in mammals. Three regions are highly conserved. Two of them appear to contain possible Walker-type nt-binding sites [Walker et al., EMBO J. 1 (1982) 945-951] and are therefore candidates for ATP-binding sites. The third region shows some similarity to a short portion of the N-proximal part of the PurA enzyme which catalyses an analogous reaction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0378-1119
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
30
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pubmed:volume |
95
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pubmed:geneSymbol |
ARG1,
arg
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
99-104
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2123815-Amino Acid Sequence,
pubmed-meshheading:2123815-Animals,
pubmed-meshheading:2123815-Archaea,
pubmed-meshheading:2123815-Argininosuccinate Synthase,
pubmed-meshheading:2123815-Base Sequence,
pubmed-meshheading:2123815-Cloning, Molecular,
pubmed-meshheading:2123815-Escherichia coli,
pubmed-meshheading:2123815-Genes, Bacterial,
pubmed-meshheading:2123815-Genes, Fungal,
pubmed-meshheading:2123815-Mammals,
pubmed-meshheading:2123815-Molecular Sequence Data,
pubmed-meshheading:2123815-Saccharomyces cerevisiae
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pubmed:year |
1990
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pubmed:articleTitle |
Sequences of the genes encoding argininosuccinate synthetase in Escherichia coli and Saccharomyces cerevisiae: comparison with methanogenic archaebacteria and mammals.
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pubmed:affiliation |
Vrije Universiteit Brussel, Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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