Linked Life Data

21237620

Source:http://linkedlifedata.com/resource/pubmed/id/21237620

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2011-6-20
pubmed:abstractText
Current approaches to dissect the molecular neurobiology of complex neuropsychiatric disorders such as schizophrenia and major depression have been rightly criticized for failing to provide benefits to patients. Improving the translational potential of our efforts will require the development and refinement of better disease models that consider a wide variety of contributing factors, such as genetic variation, gene-by-environment interactions, endophenotype or intermediate phenotype assessment, cross species analysis, sex differences, and developmental stages. During a targeted expert meeting of the European College of Neuropsychopharmacology (ECNP) in Istanbul, we addressed the opportunities and pitfalls of current translational animal models of psychiatric disorders and agreed on a series of core guidelines and recommendations that we believe will help guiding further research in this area.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1873-7862
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier B.V. and ECNP. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
532-44
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Advances in multidisciplinary and cross-species approaches to examine the neurobiology of psychiatric disorders.
pubmed:affiliation
Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands. m.j.h.kas@umcutrecht.nl
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't