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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-3-29
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pubmed:abstractText |
Studies of hepatitis C virus (HCV) infection, immunopathogenesis, and resulting liver diseases have been hampered by the lack of a small animal model. We developed humanized mice with human immune system and liver tissues to improve the studies of hepatitis C virus pathogenesis and treatment.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/AA018009,
http://linkedlifedata.com/resource/pubmed/grant/AA018372,
http://linkedlifedata.com/resource/pubmed/grant/AI076142,
http://linkedlifedata.com/resource/pubmed/grant/AI077454,
http://linkedlifedata.com/resource/pubmed/grant/R01 AI077454-01A2,
http://linkedlifedata.com/resource/pubmed/grant/R01 AI077454-04,
http://linkedlifedata.com/resource/pubmed/grant/R01 AI080432-01A2,
http://linkedlifedata.com/resource/pubmed/grant/R21 AA018009-01,
http://linkedlifedata.com/resource/pubmed/grant/R21 AA018009-02,
http://linkedlifedata.com/resource/pubmed/grant/R21 AI076142-01A1,
http://linkedlifedata.com/resource/pubmed/grant/R21 AI076142-02,
http://linkedlifedata.com/resource/pubmed/grant/RR024143,
http://linkedlifedata.com/resource/pubmed/grant/T32 AI007273
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1528-0012
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1334-44
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pubmed:meshHeading |
pubmed-meshheading:21237170-Animals,
pubmed-meshheading:21237170-Caspase 8,
pubmed-meshheading:21237170-DNA-Binding Proteins,
pubmed-meshheading:21237170-Disease Models, Animal,
pubmed-meshheading:21237170-Female,
pubmed-meshheading:21237170-Hepacivirus,
pubmed-meshheading:21237170-Hepatitis C, Chronic,
pubmed-meshheading:21237170-Hepatocytes,
pubmed-meshheading:21237170-Humans,
pubmed-meshheading:21237170-Liver Cirrhosis,
pubmed-meshheading:21237170-Mice,
pubmed-meshheading:21237170-Mice, Inbred BALB C,
pubmed-meshheading:21237170-Mice, Transgenic,
pubmed-meshheading:21237170-Stem Cells,
pubmed-meshheading:21237170-Tacrolimus Binding Proteins,
pubmed-meshheading:21237170-Transplantation, Heterologous
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pubmed:year |
2011
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pubmed:articleTitle |
A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease.
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pubmed:affiliation |
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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