rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2011-3-23
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pubmed:abstractText |
8-Nitroguanosine 3',5'-cyclic monophosphate (8-nitro-cGMP), formed nitric oxide (NO)-dependently, is a physiological second messenger, yet little is known about its role in the pathophysiology of vascular diseases. To study the pharmacological activity of 8-nitro-cGMP in diabetic mice, we compared its effects on vascular reactivity of aortas from non-diabetic and diabetic mice.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1476-5381
|
pubmed:author |
pubmed-author:AhmedKhandaker AhteshamKA,
pubmed-author:AkaikeTakaakiT,
pubmed-author:DongYi-FeiYF,
pubmed-author:FukudaMasayaM,
pubmed-author:KataokaKeiichiroK,
pubmed-author:Kim-MitsuyamaShokeiS,
pubmed-author:NakamuraTaishiT,
pubmed-author:NakoHisatoH,
pubmed-author:SawaTomohiroT,
pubmed-author:TokutomiYoshikoY,
pubmed-author:ToyamaKensukeK,
pubmed-author:YamamotoEiichiroE
|
pubmed:copyrightInfo |
© 2011 The Authors. British Journal of Pharmacology © 2011 The British Pharmacological Society.
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pubmed:issnType |
Electronic
|
pubmed:volume |
162
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1884-93
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pubmed:meshHeading |
pubmed-meshheading:21232030-Animals,
pubmed-meshheading:21232030-Aorta, Thoracic,
pubmed-meshheading:21232030-Blotting, Western,
pubmed-meshheading:21232030-Cyclic GMP,
pubmed-meshheading:21232030-Diabetes Mellitus, Type 2,
pubmed-meshheading:21232030-Dose-Response Relationship, Drug,
pubmed-meshheading:21232030-Endothelium, Vascular,
pubmed-meshheading:21232030-Male,
pubmed-meshheading:21232030-Mice,
pubmed-meshheading:21232030-Mice, Inbred C57BL,
pubmed-meshheading:21232030-Nitric Oxide Synthase Type III,
pubmed-meshheading:21232030-Obesity,
pubmed-meshheading:21232030-Phenylephrine,
pubmed-meshheading:21232030-Vasoconstriction,
pubmed-meshheading:21232030-Vasodilation
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pubmed:year |
2011
|
pubmed:articleTitle |
Vascular responses to 8-nitro-cyclic GMP in non-diabetic and diabetic mice.
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pubmed:affiliation |
Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|