Source:http://linkedlifedata.com/resource/pubmed/id/21228045
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2011-3-24
|
| pubmed:abstractText |
Since a growing number of patients after surgical repair of transposition of the great arteries (TGA) survive until adulthood the focus of attention has shifted to the management of associated long-term morbidity and quality of life (QoL). Therefore, we reviewed all patients that underwent surgical repair of TGA at our institution and compared long-term results after atrial and arterial switch operation. Between 1973 and 2000, a total of 302 patients underwent either atrial switch operation (n=222) or arterial switch operation (n=80). Mean follow-up was 14.5±10.1 years. The arterial switch repair was associated with a higher early mortality whereas long-term survival was comparable between both groups. Postoperative arrhythmias including loss of sinus rhythm and pacemaker implantation occurred significantly more often after atrial switch repair. There was a trend towards a more favourable outcome of the arterial switch group concerning freedom from re-interventions, severe systemic ventricular dysfunction and need for heart failure medication. However, also the arterial switch operation was associated with an increased incidence of loss of sinus rhythm and neo-aortic valve regurgitation during late follow-up. Health related QoL according to the SF-36 questionnaire was not significantly different between both groups and comparable to a healthy population.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
1569-9285
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
569-74
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| pubmed:meshHeading |
pubmed-meshheading:21228045-Cardiac Surgical Procedures,
pubmed-meshheading:21228045-Cardiovascular Agents,
pubmed-meshheading:21228045-Chi-Square Distribution,
pubmed-meshheading:21228045-Child, Preschool,
pubmed-meshheading:21228045-Female,
pubmed-meshheading:21228045-Germany,
pubmed-meshheading:21228045-Heart Conduction System,
pubmed-meshheading:21228045-Humans,
pubmed-meshheading:21228045-Infant,
pubmed-meshheading:21228045-Infant, Newborn,
pubmed-meshheading:21228045-Kaplan-Meier Estimate,
pubmed-meshheading:21228045-Male,
pubmed-meshheading:21228045-Quality of Life,
pubmed-meshheading:21228045-Questionnaires,
pubmed-meshheading:21228045-Reoperation,
pubmed-meshheading:21228045-Retrospective Studies,
pubmed-meshheading:21228045-Risk Assessment,
pubmed-meshheading:21228045-Risk Factors,
pubmed-meshheading:21228045-Survival Rate,
pubmed-meshheading:21228045-Survivors,
pubmed-meshheading:21228045-Time Factors,
pubmed-meshheading:21228045-Transposition of Great Vessels,
pubmed-meshheading:21228045-Treatment Outcome,
pubmed-meshheading:21228045-Vascular Surgical Procedures,
pubmed-meshheading:21228045-Ventricular Function
|
| pubmed:year |
2011
|
| pubmed:articleTitle |
Long-term morbidity and quality of life after surgical repair of transposition of the great arteries: atrial versus arterial switch operation.
|
| pubmed:affiliation |
Division of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany. goerler.adelheid@mh-hannover.de
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|