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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2011-1-26
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pubmed:abstractText |
Aortic root diameter is a clinically relevant trait due to its known relationship with the pathogenesis of aortic regurgitation and risk for aortic dissection. African Americans are an understudied population despite a particularly high burden of cardiovascular diseases. We report a genome-wide association study on aortic root diameter among African Americans enrolled in the HyperGEN study. We invoked a two-stage, mixed model procedure to jointly identify SNP allele and copy number variation effects.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-10338462,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-10903324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-10964005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-11358933,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-11525833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-11600589,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-11729172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-11835385,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-12557303,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-12817591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-15601533,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-15716907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-15882545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-16255080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-16862161,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-17386346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-17404182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-17429446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-17554300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-17660554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-17903301,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-18158348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-18523456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-18663156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-18723674,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-18776909,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-19317893,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-19424278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-19584346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-19593212,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-19812545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-19812666,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-20208535,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-20838408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-2773795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-2953289,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-7668272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-8227807,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21223598-8675263
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1755-8794
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4
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pubmed:dateRevised |
2011-7-20
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pubmed:meshHeading |
pubmed-meshheading:21223598-Adult,
pubmed-meshheading:21223598-African Americans,
pubmed-meshheading:21223598-Alleles,
pubmed-meshheading:21223598-Aorta,
pubmed-meshheading:21223598-DNA Copy Number Variations,
pubmed-meshheading:21223598-Female,
pubmed-meshheading:21223598-Genome,
pubmed-meshheading:21223598-Genome-Wide Association Study,
pubmed-meshheading:21223598-Humans,
pubmed-meshheading:21223598-Hypertension,
pubmed-meshheading:21223598-Male,
pubmed-meshheading:21223598-Middle Aged,
pubmed-meshheading:21223598-Polymorphism, Single Nucleotide
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pubmed:year |
2011
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pubmed:articleTitle |
Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study.
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pubmed:affiliation |
Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA. nwineing@uab.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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