MicroRNAs (miRNAs) are a class of small (19-25 nucleotides) noncoding RNAs that regulate the expressions of a wide variety of genes, including some involved in cancer development. Some recent studies show that DNA methylation contributes to down-regulation of microRNA-137 (miR-137) during tumorigenesis. Whether down-regulation of miR-137 also exists in gastric cancer is unknown.
Department of Medicine-Oncology, The First Affiliated Hospital, Zhengzhou University, 1 East Jianshe Road, 450000, Zhengzhou, People's Republic of China.