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pubmed-article:21220180pubmed:abstractTextThe synthesis of four new isoxazoline-based amino acids being analogues of previously described glutamate receptor ligands is reported and their affinity for ionotropic glutamate receptors is analyzed in comparison with that of selected model compounds. Molecular modelling investigations have been carried out to rationalize the interaction with the NMDA receptors.lld:pubmed
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pubmed-article:21220180pubmed:copyrightInfoCopyright © 2010 Elsevier Masson SAS. All rights reserved.lld:pubmed
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pubmed-article:21220180pubmed:articleTitleSynthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors.lld:pubmed
pubmed-article:21220180pubmed:affiliationDipartimento di Scienze Farmaceutiche Pietro Pratesi, Università degli Studi di Milano, Via Mangiagalli 25, 20133 Milano, Italy.lld:pubmed
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