Linked Life Data

21220055

Source:http://linkedlifedata.com/resource/pubmed/id/21220055

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-2-9
pubmed:abstractText
The amount of fluid displaced overnight from the legs into the neck as a consequence of lying recumbent correlates with the number of apneas and hypopneas per hour of sleep (AHI). Sedentary living promotes dependent fluid accumulation in the legs that can be counteracted by venous compression of the legs (compression stockings). We hypothesized that, in non-obese sedentary men with obstructive sleep apnea (OSA), wearing compression stockings during daytime will reduce the AHI by reducing the amount of fluid available for the displacement into the neck overnight. Polysomnography and measurement of overnight changes in leg fluid volume and neck circumference were performed at baseline and after one day of legs venous compression. The median AHI decreased from 30.9 (interquartile range 19.6-60.4) to 23.4 (12.9-31.8) (P=0.016) in association with a median 40% reduction in the change in leg fluid volume (P=0.016) and a median 42% reduction in the increase in neck circumference (P=0.016). These results provide proof-of-principle that overnight fluid displacement into the neck plays a causative role in OSA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1878-1519
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
175
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
390-3
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Effects of venous compression of the legs on overnight rostral fluid shift and obstructive sleep apnea.
pubmed:affiliation
Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Unité Fonctinonelle des Pathologies du Sommeil, 47-83 Boulevard de l’Hôpital, Paris Cedex 13, Paris, France. redstefi@inwind.it
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't