Linked Life Data

2121827

Source:http://linkedlifedata.com/resource/pubmed/id/2121827

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1990-12-12
pubmed:abstractText
Stimulation of B lymphocytes to high rate Ig secretion is accompanied by increased RNA polymerase initiation on the mu-delta gene complex as well as alterations in the sites of polymerase termination. Stimulation of Ig secretion by in vivo preactivated B lymphocytes with IL-5 seems to operate via a mechanism that only affects polymerase termination so that newly synthesized transcripts are preferentially processed to microS mRNA. The absence of increased polymerase initiation may account for previous observations indicating that IL-5 acts primarily as a terminal differentiation factor.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-1767
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
145
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3491-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Regulation of Ig H chain gene transcription by IL-5.
pubmed:affiliation
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.