Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
2011-1-10
pubmed:abstractText
In patients with HIV encephalitis, a low viral diversity between the plasma and cerebrospinal fluid (CSF) HIV-1 viruses was associated with detectable HIV RNA in plasma and a higher level of central nervous system penetration effectiveness (CPE) score, taking into account the genotypic susceptibility score of the current treatment (named balanced score). This result suggests that the CSF viruses were probably originating from the plasma. Conversely, a high viral genetic diversity was associated with an undetectable HIV RNA in plasma and low-balanced CPE, which is in favour of an autonomous replication in the central nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1473-5571
pubmed:author
pubmed:issnType
Electronic
pubmed:day
24
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2412-4
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
HIV genetic diversity between plasma and cerebrospinal fluid in patients with HIV encephalitis.
pubmed:affiliation
Université Pierre et Marie Curie-Paris 6, UMR S-943, France. cathia.soulie@psl.aphp.fr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't