Linked Life Data

21217029

Source:http://linkedlifedata.com/resource/pubmed/id/21217029

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2011-1-10
pubmed:abstractText
In the current study, the quantification of C-reactive protein (CRP) in cerebrospinal fluid (CSF) of dogs using an adapted time-resolved immunofluorimetric assay (TR-IFMA) was investigated, as well as whether the assay could be used to detect the range of CRP concentrations found in different clinical situations. Intra- and interassay coefficients of variation were below 15% in all cases. The TR-IFMA measured the CRP values in a proportional and linear manner (r ?=? 0.99); also CRP concentrations measured in CSF and in serum were significantly correlated (r ?=? 0.80, P ?=? 0.003). The limit of detection of the method was 7.1 × 10(-6) mg/l. The assay was able to detect differences in CRP concentrations in CSF of dogs with inflammatory disorders compared with dogs with spinal cord compression or idiopathic epilepsy. In conclusion, TR-IFMA constitutes a very sensitive, precise, and accurate method for the measurement of CRP concentrations in CSF.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1943-4936
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-7
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Canine C-reactive protein measurements in cerebrospinal fluid by a time-resolved immunofluorimetric assay.
pubmed:affiliation
Animal Medicine and Surgery Department, Faculty of Veterinary Medicine, University of Murcia, 30100 Espinardo Campus, Murcia, Spain.
pubmed:publicationType
Journal Article