rdf:type |
|
lifeskim:mentions |
umls-concept:C0011923,
umls-concept:C0016315,
umls-concept:C0017262,
umls-concept:C0021701,
umls-concept:C0026336,
umls-concept:C0027627,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0185117,
umls-concept:C0456904,
umls-concept:C0555952,
umls-concept:C0599894,
umls-concept:C2348628,
umls-concept:C2911684
|
pubmed:issue |
3
|
pubmed:dateCreated |
2011-2-14
|
pubmed:abstractText |
Near-infrared (NIR) fluorescence optical imaging is a promising technique to assess the extent of colorectal metastases during curative-intended surgery. However, NIR fluorescence imaging of liver metastases is highly challenging due to hepatic uptake and clearance of many fluorescent dyes. In the current study, the biodistribution and the ability to demarcate liver and peritoneal metastases were assessed during surgery in a syngeneic rat model of colorectal cancer using an integrin ?(v)?(3)-directed NIR fluorescence probe.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1532-2157
|
pubmed:author |
pubmed-author:DijkstraJJ,
pubmed-author:HuttemanMM,
pubmed-author:KaijzelE LEL,
pubmed-author:KuppenP J KPJ,
pubmed-author:LöwikC W G MCW,
pubmed-author:MieogJ S DJS,
pubmed-author:TankeH JHJ,
pubmed-author:TuQ XQX,
pubmed-author:VahrmeijerA LAL,
pubmed-author:van de VeldeC J HCJ,
pubmed-author:van der LaanA M AAM,
pubmed-author:van der VorstJ RJR
|
pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
37
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
252-7
|
pubmed:meshHeading |
pubmed-meshheading:21215590-Animals,
pubmed-meshheading:21215590-Colorectal Neoplasms,
pubmed-meshheading:21215590-Disease Models, Animal,
pubmed-meshheading:21215590-Image Processing, Computer-Assisted,
pubmed-meshheading:21215590-Integrin alphaVbeta3,
pubmed-meshheading:21215590-Intraoperative Period,
pubmed-meshheading:21215590-Liver Neoplasms,
pubmed-meshheading:21215590-Male,
pubmed-meshheading:21215590-Neoplasm Transplantation,
pubmed-meshheading:21215590-Rats,
pubmed-meshheading:21215590-Spectroscopy, Near-Infrared,
pubmed-meshheading:21215590-Tumor Cells, Cultured
|
pubmed:year |
2011
|
pubmed:articleTitle |
Intraoperative near-infrared fluorescence imaging of colorectal metastases targeting integrin ?(v)?(3) expression in a syngeneic rat model.
|
pubmed:affiliation |
Department of Surgery, Leiden University Medical Center, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|