Linked Life Data

21215302

Source:http://linkedlifedata.com/resource/pubmed/id/21215302

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-2-14
pubmed:abstractText
Laboratory rats react to a novel object with a rapid redirection of exploratory behaviour towards the source of the novelty and a subsequent decline of this neotic preference with repeated object exposure. Studies with wild Rattus norvegicus have shown that a novel object in a familiar cage results in avoidance reactions (neophobia) in those animals, but it is also well established that the wild R. norvegicus show strong aversive reactivity to a variety of high intensity stimuli. In this study we aimed to create low-stress conditions enabling the comparison of spontaneous exploratory behaviour directed at a novel object in male (age=80 days) "wild-type" WWCPS rats (n=21; fourth generation bred in captivity) and Wistar (n=24) rats. The study involved repeated placing of individual animals in the experimental chamber for 15 (6 min) trials on consecutive days. On the 11th day the novel object was introduced. Animals were tested in darkness and without human presence. Under these conditions neither WWCPS nor Wistar have shown behavioural signs of high emotional arousal, both lines have shown comparable general levels of experimental cage exploration and the positive new object exploratory reaction was observed only in Wistar rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1872-8308
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
279-83
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Response to novel object in Wistar and wild-type (WWCPS) rats.
pubmed:affiliation
Warsaw School of Social Sciences and Humanities, 19/31 Chodakowska St., 03-815 Warsaw, Poland. lukasz.tanas@swps.edu.pl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't