Linked Life Data

2121460

Source:http://linkedlifedata.com/resource/pubmed/id/2121460

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-12-6
pubmed:abstractText
The effects of Pro-thyrotropin-releasing hormone (TRH), pre-pro-TRH (53-74), pre-pro-TRH (83-106), pre-pro-TRH (115-151), pre-pro-TRH (160-169), pre-pro-TRH (178-199) and TRH on thyrotropin (TSH) and prolactin (PRL) release from the rat anterior pituitary were studied in vitro. The rat anterior pituitary was incubated in medium 199 (pH 7.4) with 1.0 mg/ml of bacitracin (medium) for 30 min. The amount of TSH and PRL release into the medium was measured by radioimmunassay. TSH and PRL release from the anterior pituitary was stimulated with the addition of TRH or pro-TRH in a dose-related manner, but not with other peptides. The findings suggest that TRH and pro-TRH stimulate TSH and PRL release from the anterior pituitary in vitro.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0013-7200
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
333-9
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Failure to demonstrate the effect of various pre-pro-TRH fragments on TSH and PRL release from rat pituitary in vitro.
pubmed:affiliation
Fourth Department of Internal Medicine, Aichi Medical University, Japan.
pubmed:publicationType
Journal Article