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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-3-10
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pubmed:abstractText |
Brain arteriovenous malformations (BAVM) are high-flow vascular lesions prone to intracranial hemorrhage (ICH). Abnormal angiogenesis is a key characteristic of BAVM tissue. Angiopoietin-like 4 (ANGPTL4), a secreted glycoprotein, is thought to be involved in angiogenesis and required for proper postnatal blood vessel partitioning. We investigated whether common single nucleotide polymorphisms (SNPs) in ANGPTL4 were associated with risk of BAVM or ICH.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1421-9786
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pubmed:author |
pubmed-author:ChenYongmeiY,
pubmed-author:HilesA MAM,
pubmed-author:KwokPui-YanPY,
pubmed-author:LawtonMichael TMT,
pubmed-author:McCullochCharles ECE,
pubmed-author:MikhakBaharB,
pubmed-author:PawlikowskaLudmilaL,
pubmed-author:PoonAnnieA,
pubmed-author:SidneyStephenS,
pubmed-author:WeinsheimerShantelS,
pubmed-author:YoungWilliam LWL,
pubmed-author:ZaroffJonathan GJG
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pubmed:copyrightInfo |
Copyright © 2011 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
338-45
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pubmed:meshHeading |
pubmed-meshheading:21212665-Adult,
pubmed-meshheading:21212665-Angiopoietins,
pubmed-meshheading:21212665-California,
pubmed-meshheading:21212665-Case-Control Studies,
pubmed-meshheading:21212665-Cerebral Angiography,
pubmed-meshheading:21212665-Chi-Square Distribution,
pubmed-meshheading:21212665-European Continental Ancestry Group,
pubmed-meshheading:21212665-Female,
pubmed-meshheading:21212665-Gene Frequency,
pubmed-meshheading:21212665-Genetic Predisposition to Disease,
pubmed-meshheading:21212665-Haplotypes,
pubmed-meshheading:21212665-Humans,
pubmed-meshheading:21212665-Intracranial Arteriovenous Malformations,
pubmed-meshheading:21212665-Intracranial Hemorrhages,
pubmed-meshheading:21212665-Logistic Models,
pubmed-meshheading:21212665-Magnetic Resonance Angiography,
pubmed-meshheading:21212665-Male,
pubmed-meshheading:21212665-Middle Aged,
pubmed-meshheading:21212665-Odds Ratio,
pubmed-meshheading:21212665-Phenotype,
pubmed-meshheading:21212665-Polymorphism, Single Nucleotide,
pubmed-meshheading:21212665-Registries,
pubmed-meshheading:21212665-Risk Assessment,
pubmed-meshheading:21212665-Risk Factors,
pubmed-meshheading:21212665-Tomography, X-Ray Computed,
pubmed-meshheading:21212665-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Angiopoietin-like 4 (ANGPTL4) gene polymorphisms and risk of brain arteriovenous malformations.
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pubmed:affiliation |
Center for Cerebrovascular Research, Department of Anesthesia and Perioperative Care, University of California, San Francisco, 94110, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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