21209875

Source:http://linkedlifedata.com/resource/pubmed/id/21209875

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0005682, umls-concept:C0021368, umls-concept:C0024429, umls-concept:C0030685, umls-concept:C0040018, umls-concept:C0041904, umls-concept:C0205263, umls-concept:C0227598, umls-concept:C0312359, umls-concept:C0391871, umls-concept:C0680255, umls-concept:C1283071, umls-concept:C1334507, umls-concept:C1880177, umls-concept:C1963578
pubmed:issue	12
pubmed:dateCreated	2011-1-6
pubmed:abstractText	Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine expressed by urothelial cells that mediates bladder inflammation. We investigated the effect of stimulation with thrombin, a Protease Activated Receptor-1 (PAR1) agonist, on MIF release and MIF mRNA upregulation in urothelial cells.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/DK075059
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101285081
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cytokines, http://linkedlifedata.com/resource/pubmed/chemical/Macrophage Migration-Inhibitory..., http://linkedlifedata.com/resource/pubmed/chemical/Receptor, PAR-1, http://linkedlifedata.com/resource/pubmed/chemical/Thrombin
pubmed:status	MEDLINE
pubmed:issn	1932-6203
pubmed:author	pubmed-author:BraleyAlexander EAE, pubmed-author:Meyer-SieglerKatherine LKL, pubmed-author:VeraPedro LPL, pubmed-author:WolfeTerra ETE
pubmed:issnType	Electronic
pubmed:volume	5
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e15904
pubmed:dateRevised	2011-7-20
pubmed:meshHeading	pubmed-meshheading:21209875-Animals, pubmed-meshheading:21209875-Cell Line, pubmed-meshheading:21209875-Cytokines, pubmed-meshheading:21209875-Dose-Response Relationship, Drug, pubmed-meshheading:21209875-Humans, pubmed-meshheading:21209875-Inflammation, pubmed-meshheading:21209875-Macrophage Migration-Inhibitory Factors, pubmed-meshheading:21209875-Male, pubmed-meshheading:21209875-Rats, pubmed-meshheading:21209875-Receptor, PAR-1, pubmed-meshheading:21209875-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:21209875-Thrombin, pubmed-meshheading:21209875-Up-Regulation, pubmed-meshheading:21209875-Urinary Bladder, pubmed-meshheading:21209875-Urothelium
pubmed:year	2010
pubmed:articleTitle	Thrombin induces macrophage migration inhibitory factor release and upregulation in urothelium: a possible contribution to bladder inflammation.
pubmed:affiliation	Research and Development, The Bay Pines VA Healthcare System, Bay Pines, Florida, United States of America. pvera@health.usf.edu
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural