Linked Life Data

2120886

Source:http://linkedlifedata.com/resource/pubmed/id/2120886

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-11-14
pubmed:abstractText
Ten cases of chronic myeloproliferative diseases with myelofibrosis and circulating megakaryoblasts have been studied. The megakaryoblasts were recognized by the presence of megakaryocyte-platelet-related cell surface antigens, detected by an immuno-electron-microscopic method. They showed a tendency to develop from 'lymphocyte-like' mononuclear cells to relatively mature megakaryocytes. In these latter cells, the cytoplasm was abundant and contained specific organelles and cytoplasmic blebs. Several characteristic features were observed during the maturation of the megakaryoblasts: (1) cells of the megakaryocytic lineage represented by microforms, (2) dysplastic platelets (giant, nucleated and agranular platelets), (3) the shedding of dysplastic platelets brought about by cytoplasmatic membrane inclusions and (4) naked nuclei.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5792
pubmed:author
pubmed:issnType
Print
pubmed:volume
84
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-63
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Circulating megakaryoblasts in chronic myeloproliferative diseases. An immunoelectron-microscopic study.
pubmed:affiliation
Department of Pathology, University Medical School of Pécs, Hungary.
pubmed:publicationType
Journal Article