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rdf:type |
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lifeskim:mentions |
umls-concept:C0007320,
umls-concept:C0008625,
umls-concept:C0023484,
umls-concept:C0023693,
umls-concept:C0036536,
umls-concept:C0036537,
umls-concept:C0085973,
umls-concept:C0205225,
umls-concept:C0282441,
umls-concept:C0337112,
umls-concept:C0439064,
umls-concept:C1522326,
umls-concept:C1524075
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pubmed:issue |
3
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pubmed:dateCreated |
2011-1-5
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pubmed:abstractText |
Primary plasma cell leukemia is a rare form of plasma cell dyscrasia. We present a case which had leukocytosis with numerous circulating plasma cells in the peripheral blood. Flow cytometry revealed an unusual CD117 expression. Free light chain analysis in the serum showed a markedly elevated level of free lambda light chains. Radiography did not reveal any lytic lesions. Fluorescent in-situ hybridization analysis revealed deletion of 13q14.3 and t(4;14)/t(11;14), while the cytogenetic analysis was normal. The patient was given chemotherapy and was subjected to autologous stem cell transplant, after which she is in complete remission till date.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-10626149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-1511063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-15795922,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-17325841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-17908524,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-18509355,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-2697596,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-3116673,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-4821776,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-6401225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-8343266,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-8907265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21206718-9920853
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pubmed:language |
eng
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pubmed:journal |
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pubmed:status |
PubMed-not-MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0975-2129
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96-100
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pubmed:dateRevised |
2011-7-20
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pubmed:year |
2010
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pubmed:articleTitle |
Primary plasma cell leukemia with light chain secretion and multiple chromosomal abnormalities: How successfully treated? - A case report with review of literature.
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pubmed:affiliation |
Department of Laboratory Medicine, Indo-American Cancer Institute and Research Centre, Hyderabad, India.
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pubmed:publicationType |
Journal Article
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