Source:http://linkedlifedata.com/resource/pubmed/id/21204579
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2011-2-9
|
pubmed:abstractText |
Metal nanoparticles play a key role in sensing and imaging. Here we demonstrate the detection of metal particles down to 5 nm in size with a signal-to-noise ratio of ?7 using interferometric cross-polarization microscopy at ultralow excitation powers (?1 ?W) compatible with single molecule detection. The method is background-free and induces no heating as it operates far from plasmonic resonance. The combination of unlimited observation time and protein-sized metal nanoparticles has great potential for biophysical applications.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1530-6992
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
9
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
541-7
|
pubmed:meshHeading | |
pubmed:year |
2011
|
pubmed:articleTitle |
Background-free detection of single 5 nm nanoparticles through interferometric cross-polarization microscopy.
|
pubmed:affiliation |
H H Wills Physics Laboratory, University of Bristol, Bristol, United Kingdom.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|