|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2011-1-4
|
|
pubmed:abstractText |
In cultured prostate cancer cells, down-regulation of epidermal growth factor receptor (EGFR) has been implicated in mediating the antiproliferative effect of the endogenous cannabinoid (CB) ligand anandamide. Using a well-characterised cohort of prostate cancer patients, we have previously reported that expression levels of phosphorylated EGFR (pEGFR-IR) and CB(1) receptor (CB(1)IR) in tumour tissue at diagnosis are markers of disease-specific survival, but it is not known whether the two markers interact in terms of their influence on disease severity at diagnosis and disease outcome.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-10614630,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-11942960,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-12746841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-14675774,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-15475446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-15604240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-15753356,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-15919052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-16195239,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-16410346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-17068343,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-17376185,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-17943729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-17952650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-18566995,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-18676872,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-19056257,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-19229996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-19285265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-19690545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-19889794,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-20090845,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-20130423,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-20145160,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-20370711,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-20531936,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-20808855,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21203460-8472349
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1932-6203
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
5
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
e15205
|
|
pubmed:dateRevised |
2011-7-20
|
|
pubmed:meshHeading |
pubmed-meshheading:21203460-Cell Line, Tumor,
pubmed-meshheading:21203460-Gene Deletion,
pubmed-meshheading:21203460-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21203460-Humans,
pubmed-meshheading:21203460-Immunohistochemistry,
pubmed-meshheading:21203460-Male,
pubmed-meshheading:21203460-Neoplasm Metastasis,
pubmed-meshheading:21203460-Phosphorylation,
pubmed-meshheading:21203460-Prognosis,
pubmed-meshheading:21203460-Proportional Hazards Models,
pubmed-meshheading:21203460-Prostatic Neoplasms,
pubmed-meshheading:21203460-ROC Curve,
pubmed-meshheading:21203460-Receptor, Cannabinoid, CB1,
pubmed-meshheading:21203460-Receptor, Epidermal Growth Factor,
pubmed-meshheading:21203460-Regression Analysis
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Tumour Cannabinoid CB(1) receptor and phosphorylated epidermal growth factor receptor expression are additive prognostic markers for prostate cancer.
|
|
pubmed:affiliation |
Department of Pharmacology and Clinical Neuroscience, Pharmacology, Umeå University, Umeå, Sweden.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
