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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-30
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pubmed:abstractText |
Sertoli cells (SCs) provide an immunoprotective environment to pancreatic islet grafts for treatment of insulin-dependent diabetes. Aim of this work was to verify whether intraperitoneal graft of SCs, enveloped in barium alginate-based microcapsules, would reverse overt spontaneous diabetes in nonobese diabetic (NOD) mice by eliciting generation of newly formed functional islets ?-cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Autoantibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Basic Helix-Loop-Helix...,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Eye Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Glucagon,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Neurod1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Neurog3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/PAX6 protein,
http://linkedlifedata.com/resource/pubmed/chemical/Paired Box Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Pap protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Pax4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-kit,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Somatostatin,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/pancreatic and duodenal homeobox 1...
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1534-6080
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pubmed:author |
pubmed-author:AratoIvaI,
pubmed-author:BecchettiEnnioE,
pubmed-author:CalafioreRiccardoR,
pubmed-author:CalvittiMarioM,
pubmed-author:FalabellaGiuliaG,
pubmed-author:FallarinoFrancescaF,
pubmed-author:GrohmannUrsulaU,
pubmed-author:LucaGiovanniG,
pubmed-author:MancusoFrancescaF,
pubmed-author:NastruzziClaudioC,
pubmed-author:PuccettiPaoloP
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1352-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21197711-Animals,
pubmed-meshheading:21197711-Autoantibodies,
pubmed-meshheading:21197711-Basic Helix-Loop-Helix Transcription Factors,
pubmed-meshheading:21197711-Blood Glucose,
pubmed-meshheading:21197711-Diabetes Mellitus, Type 1,
pubmed-meshheading:21197711-Eye Proteins,
pubmed-meshheading:21197711-Glucagon,
pubmed-meshheading:21197711-Homeodomain Proteins,
pubmed-meshheading:21197711-Immunohistochemistry,
pubmed-meshheading:21197711-Insulin,
pubmed-meshheading:21197711-Insulin Antibodies,
pubmed-meshheading:21197711-Insulin-Secreting Cells,
pubmed-meshheading:21197711-Male,
pubmed-meshheading:21197711-Mice,
pubmed-meshheading:21197711-Mice, Inbred NOD,
pubmed-meshheading:21197711-Nerve Tissue Proteins,
pubmed-meshheading:21197711-Paired Box Transcription Factors,
pubmed-meshheading:21197711-Polymerase Chain Reaction,
pubmed-meshheading:21197711-Proteins,
pubmed-meshheading:21197711-Proto-Oncogene Proteins c-kit,
pubmed-meshheading:21197711-Repressor Proteins,
pubmed-meshheading:21197711-Sertoli Cells,
pubmed-meshheading:21197711-Somatostatin,
pubmed-meshheading:21197711-Testis,
pubmed-meshheading:21197711-Trans-Activators,
pubmed-meshheading:21197711-Transplantation, Heterologous
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pubmed:year |
2010
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pubmed:articleTitle |
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells.
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pubmed:affiliation |
Department of Experimental Medicine, University of Perugia, Perugia, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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