Linked Life Data

2119563

Source:http://linkedlifedata.com/resource/pubmed/id/2119563

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-10-26
pubmed:abstractText
Using automated measurements of kappa (kappa) and lambda (lambda) light chain and IgG, IgA and IgM concentrations we assessed the ability of the kappa/lambda ratio and the heavy/light chain ratio to identify and type monoclonal components which had been previously identified by serum protein electrophoresis and immunoelectrophoresis. We examined 1151 samples, of which 277 contained monoclonal components; 90% of the monoclonal proteins could be identified by this approach, of which 95% were correctly typed. In addition 19 of 874 samples without monoclonal components showed an abnormal kappa/lambda ratio. We assessed the ability of the immunochemical evaluation to calculate monoclonal component concentration and then compared the results to the scanning densitometry of serum protein electrophoresis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0004-5632
pubmed:author
pubmed:issnType
Print
pubmed:volume
27 ( Pt 4)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
327-34
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
An immunochemical evaluation for the identification and typing of monoclonal proteins.
pubmed:affiliation
Supraregional Protein Reference Unit, Royal Infirmary, Cardiff, Wales, UK.
pubmed:publicationType
Journal Article, Comparative Study