|
pubmed:abstractText |
In our previous study concerning the genetic relationship among H10 avian influenza viruses with different pathogenicity in mink (Mustela vison), we found that these differences were related to amino acid variations in the NS1 protein. In this study, we extend our previous work to further investigate the effect of the NS1 from different gene pools on type I IFN promoter activity, the production of IFN-?, as well as the expression of the IFN-? mRNA in response to poly I:C.
|
|
pubmed:affiliation |
Swedish University of Agricultural Sciences (SLU), Department of Biomedical Sciences and Veterinary Public Health, Section of Virology, SLU, Ulls Väg 2B, SE-75189 Uppsala, Sweden. siamak.zohari@sva.se
|
