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rdf:type |
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lifeskim:mentions |
umls-concept:C0001675,
umls-concept:C0010674,
umls-concept:C0030705,
umls-concept:C0205147,
umls-concept:C0205409,
umls-concept:C0318157,
umls-concept:C1519068,
umls-concept:C1521991,
umls-concept:C1533693,
umls-concept:C1708726,
umls-concept:C1880022
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pubmed:issue |
3
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pubmed:dateCreated |
2011-3-11
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pubmed:abstractText |
Ciprofloxacin is the most frequently used member of the fluoroquinolones during initial eradication therapy of Pseudomonas aeruginosa, as well as during acute pulmonary exacerbations. However, its long-term effect on the susceptibility of the commensal flora within the cystic fibrosis (CF) airways has not yet been examined. The aim of this study was therefore to examine the consequence of oral ciprofloxacin usage on the resistance of the commensal viridans group streptococci (VGS), in terms of MICs and mutational analysis of the quinolone resistance-determining regions (QRDRs).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1460-2091
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pubmed:author |
pubmed-author:CoulterWilson AWA,
pubmed-author:DooleyJames S GJS,
pubmed-author:ElbornJ StuartJS,
pubmed-author:GoldsmithColin ECE,
pubmed-author:LoweryColm JCJ,
pubmed-author:MaedaYasunoriY,
pubmed-author:MasonCharleneC,
pubmed-author:MatsudaMotooM,
pubmed-author:MillarB CherieBC,
pubmed-author:MooreJohn EJE,
pubmed-author:MurayamaMayumiM,
pubmed-author:RendallJacqueline CJC
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pubmed:issnType |
Electronic
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
476-86
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pubmed:meshHeading |
pubmed-meshheading:21193474-Adult,
pubmed-meshheading:21193474-Anti-Bacterial Agents,
pubmed-meshheading:21193474-Ciprofloxacin,
pubmed-meshheading:21193474-Cystic Fibrosis,
pubmed-meshheading:21193474-DNA, Bacterial,
pubmed-meshheading:21193474-DNA Gyrase,
pubmed-meshheading:21193474-DNA Topoisomerase IV,
pubmed-meshheading:21193474-Drug Resistance, Bacterial,
pubmed-meshheading:21193474-Drug Utilization,
pubmed-meshheading:21193474-Female,
pubmed-meshheading:21193474-Humans,
pubmed-meshheading:21193474-Male,
pubmed-meshheading:21193474-Microbial Sensitivity Tests,
pubmed-meshheading:21193474-Middle Aged,
pubmed-meshheading:21193474-Quinolones,
pubmed-meshheading:21193474-Sequence Analysis, DNA,
pubmed-meshheading:21193474-Streptococcal Infections,
pubmed-meshheading:21193474-Viridans Streptococci
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pubmed:year |
2011
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pubmed:articleTitle |
Molecular characterization and phylogenetic analysis of quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC and parE gene loci in viridans group streptococci isolated from adult patients with cystic fibrosis.
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pubmed:affiliation |
Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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