Linked Life Data

21190269

Source:http://linkedlifedata.com/resource/pubmed/id/21190269

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-12-30
pubmed:abstractText
Maghemite particles are used as T? contrast agents for magnetic resonance imaging, especially for molecular and cellular imaging. Linear clusters of particles - called nanoworms - were recently developed to enhance the targeting efficiency. In this work, the magnetic and NMR relaxation properties of these nanoworms are studied at multiple magnetic fields. After the usual saturation at 0.5 T, the magnetization of the worms is still increasing, which results in an appreciable increase of the transverse relaxivity at high magnetic fields. The obtained relaxivities are typical of superparamagnetic particles of iron oxide (SPIOs). The transverse relaxation of the worms is clearly more efficient than for the isolated grains, which is confirmed by computer simulations. At high field, the longitudinal relaxation of the worms is less pronounced than for the grains, as expected for SPIOs. The nanoworms thus constitute a promising T? agent for cellular and molecular imaging.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1555-4317
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 John Wiley & Sons, Ltd.
pubmed:issnType
Electronic
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
318-22
pubmed:meshHeading
pubmed:articleTitle
NMR relaxation and magnetic properties of superparamagnetic nanoworms.
pubmed:affiliation
Biological Physics Department, Université de Mons, Mons, Belgium. yves.gossuin@umons.ac.be
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural