Source:http://linkedlifedata.com/resource/pubmed/id/21188972
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2011-1-31
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pubmed:abstractText |
A regioselective intramolecular cyclization/halogenation reaction of N-alkoxy-o-alkynylbenzamides with CuCl(2)/NCS was developed. The corresponding 3-(chloromethylene)isobenzofuran-1-ones were exclusively obtained via 5-exo-dig cyclization in moderate to excellent yields within 0.5-1 h. This approach has been successfully used to synthesize a biaryl compound by the Suzuki-Miyaura reaction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkynes,
http://linkedlifedata.com/resource/pubmed/chemical/Benzamides,
http://linkedlifedata.com/resource/pubmed/chemical/Benzofurans,
http://linkedlifedata.com/resource/pubmed/chemical/Copper,
http://linkedlifedata.com/resource/pubmed/chemical/cupric chloride
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1523-7052
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
4
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
518-21
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pubmed:meshHeading | |
pubmed:year |
2011
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pubmed:articleTitle |
Copper(II)chloride-mediated cyclization reaction of N-alkoxy-ortho-alkynylbenzamides.
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pubmed:affiliation |
Kobe Pharmaceutical University, Motoyamakita, Higashinada, Kobe, Hyogo 658-8558, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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