(11)C-Methionine positron emission tomography (MET-PET) has been used to distinguish brain tumor recurrence from radiation necrosis. Because the spatial resolution of conventional PET scanners is low, partial volume effect (PVE) may decrease the detectability of small tumor recurrence. The aim of this study is to investigate the diagnostic value of MET-PET upon semiquantitative analyses in particular PVE-affected small lesions.
Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, North 15th, West 7th, Kitaku, Sapporo, 060-8638, Japan. shozo@med.hokudai.ac.jp