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rdf:type |
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lifeskim:mentions |
umls-concept:C0007090,
umls-concept:C0010762,
umls-concept:C0014417,
umls-concept:C0020362,
umls-concept:C0020792,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0045906,
umls-concept:C0046435,
umls-concept:C0086418,
umls-concept:C0870883
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pubmed:dateCreated |
2011-3-8
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pubmed:abstractText |
N-(2-methoxyphenyl)hydroxylamine is a human metabolite of two industrial and environmental pollutants and bladder carcinogens 2-methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole). Metabolism of N-(2-methoxyphenyl)hydroxylamine by rat hepatic microsomes and identification of the major microsomal enzymes participating in this process are aims of this study.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-anisidine,
http://linkedlifedata.com/resource/pubmed/chemical/2-nitroanisole,
http://linkedlifedata.com/resource/pubmed/chemical/Aniline Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Anisoles,
http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases,
http://linkedlifedata.com/resource/pubmed/chemical/Carcinogens,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP2E1,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System,
http://linkedlifedata.com/resource/pubmed/chemical/Environmental Pollutants,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxylamine,
http://linkedlifedata.com/resource/pubmed/chemical/Steroid Hydroxylases,
http://linkedlifedata.com/resource/pubmed/chemical/cytochrome P-450 CYP2C subfamily,
http://linkedlifedata.com/resource/pubmed/chemical/steroid hormone 7-alpha-hydroxylase
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pubmed:status |
MEDLINE
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pubmed:issn |
0172-780X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
31 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
36-45
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pubmed:meshHeading |
pubmed-meshheading:21187827-Aniline Compounds,
pubmed-meshheading:21187827-Animals,
pubmed-meshheading:21187827-Anisoles,
pubmed-meshheading:21187827-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:21187827-Carcinogens,
pubmed-meshheading:21187827-Cytochrome P-450 CYP2E1,
pubmed-meshheading:21187827-Cytochrome P-450 Enzyme System,
pubmed-meshheading:21187827-Environmental Pollutants,
pubmed-meshheading:21187827-Hydroxylamine,
pubmed-meshheading:21187827-Male,
pubmed-meshheading:21187827-Microsomes, Liver,
pubmed-meshheading:21187827-Models, Animal,
pubmed-meshheading:21187827-Oxidation-Reduction,
pubmed-meshheading:21187827-Rats,
pubmed-meshheading:21187827-Rats, Wistar,
pubmed-meshheading:21187827-Steroid Hydroxylases
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pubmed:year |
2010
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pubmed:articleTitle |
Identification of rat cytochromes P450 metabolizing N-(2-methoxyphenyl)hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole.
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pubmed:affiliation |
Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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