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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-1-28
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pubmed:abstractText |
Genetic variation may contribute to differential gene expression in the brain of individuals with psychiatric disorders. To test this hypothesis, we identified genes that were differentially expressed in individuals with bipolar disorder, along with nearby single nucleotide polymorphisms (SNPs) that were associated with expression of the same genes. We then tested these SNPs for association with bipolar disorder in large case-control samples.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1873-2402
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
353-9
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pubmed:meshHeading |
pubmed-meshheading:21185011-Alleles,
pubmed-meshheading:21185011-Bipolar Disorder,
pubmed-meshheading:21185011-Cytoskeletal Proteins,
pubmed-meshheading:21185011-Databases, Genetic,
pubmed-meshheading:21185011-Female,
pubmed-meshheading:21185011-Gene Expression,
pubmed-meshheading:21185011-Gene Frequency,
pubmed-meshheading:21185011-Genetic Association Studies,
pubmed-meshheading:21185011-Genetic Predisposition to Disease,
pubmed-meshheading:21185011-Genetic Variation,
pubmed-meshheading:21185011-Genotype,
pubmed-meshheading:21185011-Haplotypes,
pubmed-meshheading:21185011-Humans,
pubmed-meshheading:21185011-Male,
pubmed-meshheading:21185011-Neuropeptides,
pubmed-meshheading:21185011-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:21185011-Polymorphism, Single Nucleotide,
pubmed-meshheading:21185011-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2011
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pubmed:articleTitle |
Gene expression and genetic variation data implicate PCLO in bipolar disorder.
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pubmed:affiliation |
Stanley Laboratory of Brain Research, Rockville, Maryland, USA. kwang.choi@usuhs.mil
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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