Source:http://linkedlifedata.com/resource/pubmed/id/21184832
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-2-8
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pubmed:abstractText |
The catechol-O-methyltransferase (COMT) Val(108/158)Met polymorphism of the dopamine system is essential for prefrontal cortex processing capacity and efficiency. In addition, dopaminergic neurotransmission is also associated with the sensory gating phenomenon protecting the cerebral cortex from information overload. It is however unclear if COMT genotype as a predictor of prefrontal efficiency modulates sensory gating on the level of the auditory cortex, i.e. the gating of the auditory evoked P50 and N100 components.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1095-9572
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
818-24
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pubmed:meshHeading |
pubmed-meshheading:21184832-Adult,
pubmed-meshheading:21184832-Brain,
pubmed-meshheading:21184832-Catechol O-Methyltransferase,
pubmed-meshheading:21184832-Electroencephalography,
pubmed-meshheading:21184832-Evoked Potentials, Auditory,
pubmed-meshheading:21184832-Female,
pubmed-meshheading:21184832-Genotype,
pubmed-meshheading:21184832-Humans,
pubmed-meshheading:21184832-Male,
pubmed-meshheading:21184832-Polymerase Chain Reaction,
pubmed-meshheading:21184832-Polymorphism, Single Nucleotide,
pubmed-meshheading:21184832-Sensory Gating
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pubmed:year |
2011
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pubmed:articleTitle |
COMT Val108/158Met genotype modulates human sensory gating.
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pubmed:affiliation |
Clinic for Psychiatry and Psychotherapy, Charité University Medicine, Campus Mitte, Berlin, Germany. tomislav.majic@charite.de
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pubmed:publicationType |
Journal Article
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