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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-2-24
pubmed:abstractText
Candidemia is a well-recognized complication of hospital stay, especially in critically ill patients. There is not a general consensus that predictors for candidemia in cardiosurgical intensive care unit (cICU) are different from a general ICU and it has been reported that cardiopulmonary bypass time is a specific risk factor in the cICU. We performed a prospective study to evaluate the main predictors for candidemia in patients admitted to the cICU. Included patients were adults admitted between July 2005 and December 2007 with an ICU-length of stay (ICU-LOS) ?48 hours after cardiac surgery. Exclusion criteria were solid organ or bone marrow transplants, previous diagnosis of candidemia or other invasive infections and ICU stay before surgery. A multiple regression analysis was performed to identify the risk factors. Among 1955 patients admitted to the cICU, 345 were enrolled. Only 26 patients (1.3%) had candidemia after an ICU-LOS of 20 days (inter-quartile range, IQR 8-49 days). Total parenteral nutrition [odds ratio (OR)=9.56; confidence interval (CI)=1.741-52.534], severe sepsis (OR=4.20; CI=1.292-13.667), simplified acute physiology score II (OR=1.16; CI=1.052-1.278) and ICU-LOS >20 days (OR=6.38; CI=1.971-20.660) were independent predictors of candidemia. Patients undergoing cardiac surgery developed candidemia late after cICU admission and the independent predictors were similar to the general ICU.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1569-9285
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
374-8
pubmed:meshHeading
pubmed-meshheading:21183505-Adult, pubmed-meshheading:21183505-Aged, pubmed-meshheading:21183505-Aged, 80 and over, pubmed-meshheading:21183505-Candidemia, pubmed-meshheading:21183505-Cardiac Surgical Procedures, pubmed-meshheading:21183505-Chi-Square Distribution, pubmed-meshheading:21183505-Cross Infection, pubmed-meshheading:21183505-Female, pubmed-meshheading:21183505-Humans, pubmed-meshheading:21183505-Intensive Care Units, pubmed-meshheading:21183505-Italy, pubmed-meshheading:21183505-Kaplan-Meier Estimate, pubmed-meshheading:21183505-Length of Stay, pubmed-meshheading:21183505-Logistic Models, pubmed-meshheading:21183505-Male, pubmed-meshheading:21183505-Middle Aged, pubmed-meshheading:21183505-Odds Ratio, pubmed-meshheading:21183505-Proportional Hazards Models, pubmed-meshheading:21183505-Prospective Studies, pubmed-meshheading:21183505-Risk Assessment, pubmed-meshheading:21183505-Risk Factors, pubmed-meshheading:21183505-Time Factors
pubmed:year
2011
pubmed:articleTitle
Candidemia after cardiac surgery in the intensive care unit: an observational study.
pubmed:affiliation
Department of Anesthesia and Intensive Care Medicine, San Giovanni Battista Hospital, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy. daniela.pasero@unito.it
pubmed:publicationType
Journal Article