Source:http://linkedlifedata.com/resource/pubmed/id/21183505
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2011-2-24
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pubmed:abstractText |
Candidemia is a well-recognized complication of hospital stay, especially in critically ill patients. There is not a general consensus that predictors for candidemia in cardiosurgical intensive care unit (cICU) are different from a general ICU and it has been reported that cardiopulmonary bypass time is a specific risk factor in the cICU. We performed a prospective study to evaluate the main predictors for candidemia in patients admitted to the cICU. Included patients were adults admitted between July 2005 and December 2007 with an ICU-length of stay (ICU-LOS) ?48 hours after cardiac surgery. Exclusion criteria were solid organ or bone marrow transplants, previous diagnosis of candidemia or other invasive infections and ICU stay before surgery. A multiple regression analysis was performed to identify the risk factors. Among 1955 patients admitted to the cICU, 345 were enrolled. Only 26 patients (1.3%) had candidemia after an ICU-LOS of 20 days (inter-quartile range, IQR 8-49 days). Total parenteral nutrition [odds ratio (OR)=9.56; confidence interval (CI)=1.741-52.534], severe sepsis (OR=4.20; CI=1.292-13.667), simplified acute physiology score II (OR=1.16; CI=1.052-1.278) and ICU-LOS >20 days (OR=6.38; CI=1.971-20.660) were independent predictors of candidemia. Patients undergoing cardiac surgery developed candidemia late after cICU admission and the independent predictors were similar to the general ICU.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1569-9285
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
374-8
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pubmed:meshHeading |
pubmed-meshheading:21183505-Adult,
pubmed-meshheading:21183505-Aged,
pubmed-meshheading:21183505-Aged, 80 and over,
pubmed-meshheading:21183505-Candidemia,
pubmed-meshheading:21183505-Cardiac Surgical Procedures,
pubmed-meshheading:21183505-Chi-Square Distribution,
pubmed-meshheading:21183505-Cross Infection,
pubmed-meshheading:21183505-Female,
pubmed-meshheading:21183505-Humans,
pubmed-meshheading:21183505-Intensive Care Units,
pubmed-meshheading:21183505-Italy,
pubmed-meshheading:21183505-Kaplan-Meier Estimate,
pubmed-meshheading:21183505-Length of Stay,
pubmed-meshheading:21183505-Logistic Models,
pubmed-meshheading:21183505-Male,
pubmed-meshheading:21183505-Middle Aged,
pubmed-meshheading:21183505-Odds Ratio,
pubmed-meshheading:21183505-Proportional Hazards Models,
pubmed-meshheading:21183505-Prospective Studies,
pubmed-meshheading:21183505-Risk Assessment,
pubmed-meshheading:21183505-Risk Factors,
pubmed-meshheading:21183505-Time Factors
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pubmed:year |
2011
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pubmed:articleTitle |
Candidemia after cardiac surgery in the intensive care unit: an observational study.
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pubmed:affiliation |
Department of Anesthesia and Intensive Care Medicine, San Giovanni Battista Hospital, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy. daniela.pasero@unito.it
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pubmed:publicationType |
Journal Article
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