Linked Life Data

21181914

Source:http://linkedlifedata.com/resource/pubmed/id/21181914

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:21181914rdf:typepubmed:Citationlld:pubmed
pubmed-article:21181914lifeskim:mentionsumls-concept:C0376325lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C0021311lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C0005767lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C1512080lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C0003261lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C0042196lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C0848332lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C2827485lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C1524063lld:lifeskim
pubmed-article:21181914lifeskim:mentionsumls-concept:C0205296lld:lifeskim
pubmed-article:21181914pubmed:issue2lld:pubmed
pubmed-article:21181914pubmed:dateCreated2010-12-24lld:pubmed
pubmed-article:21181914pubmed:abstractTextDuring recent years, vaccination against hepatitis A has been implemented in several countries. It is expected that the increase in mass vaccination against hepatitis A will eventually result in a decreased prevalence of anti-HAV antibodies in the general population. For this reason, a suitable clinical sample for diagnosis of hepatitis A must be sufficiently sensitive to enable detection of lower antibodies titers. In this study, the feasibility of using dried blood spots (DBS) was assessed for the detection of anti-HAV antibodies after a natural infection and vaccination. Seventy-four DBS and paired plasma samples were obtained from a group of college students for a cross-sectional hepatitis A seroepidemiological study. Forty-six students seronegative for anti-HAV were selected randomly and immunized with an inactivated hepatitis A vaccine using an 0-6 month schedule. Seroconversion was monitored in paired plasma and DBS samples 6 months after the first dose followed by a period of 8 and 24 months after the second dose. A strong correlation between OD/CO rates of paired plasma and DBS samples for the detection of anti-HAV was observed. The sensitivity and specificity of the DBS compared with plasma for the detection of anti-HAV antibodies after natural infection was 100%. The sensitivity of DBS in samples collected 24 months after the second dose of hepatitis A vaccine was 95.4%. The results showed that DBS samples can be used for the detection of anti-HAV antibodies both after natural infection or vaccination.lld:pubmed
pubmed-article:21181914pubmed:languageenglld:pubmed
pubmed-article:21181914pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21181914pubmed:citationSubsetIMlld:pubmed
pubmed-article:21181914pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21181914pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21181914pubmed:statusMEDLINElld:pubmed
pubmed-article:21181914pubmed:monthFeblld:pubmed
pubmed-article:21181914pubmed:issn1096-9071lld:pubmed
pubmed-article:21181914pubmed:authorpubmed-author:FreireMMlld:pubmed
pubmed-article:21181914pubmed:authorpubmed-author:ChouF CFClld:pubmed
pubmed-article:21181914pubmed:authorpubmed-author:VitralC LCLlld:pubmed
pubmed-article:21181914pubmed:authorpubmed-author:PintoM AMAlld:pubmed
pubmed-article:21181914pubmed:authorpubmed-author:RochaA MAMlld:pubmed
pubmed-article:21181914pubmed:authorpubmed-author:GasparL PLPlld:pubmed
pubmed-article:21181914pubmed:authorpubmed-author:MelgaçoJ GJGlld:pubmed
pubmed-article:21181914pubmed:authorpubmed-author:LimaS M BSMlld:pubmed
pubmed-article:21181914pubmed:copyrightInfo2010 Wiley-Liss, Inc.lld:pubmed
pubmed-article:21181914pubmed:issnTypeElectroniclld:pubmed
pubmed-article:21181914pubmed:volume83lld:pubmed
pubmed-article:21181914pubmed:ownerNLMlld:pubmed
pubmed-article:21181914pubmed:authorsCompleteYlld:pubmed
pubmed-article:21181914pubmed:pagination208-17lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:meshHeadingpubmed-meshheading:21181914...lld:pubmed
pubmed-article:21181914pubmed:year2011lld:pubmed
pubmed-article:21181914pubmed:articleTitleThe use of dried blood spots for assessing antibody response to hepatitis A virus after natural infection and vaccination.lld:pubmed
pubmed-article:21181914pubmed:affiliationDepartment of Microbiology and Parasitology-Biomedical Institute, Federal Fluminense University, Niterói, Brazil.lld:pubmed
pubmed-article:21181914pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21181914pubmed:publicationTypeRandomized Controlled Triallld:pubmed
pubmed-article:21181914pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed