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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-23
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pubmed:abstractText |
The etiology of Parkinson disease (PD) has yet to be fully elucidated. We examined the consequences of injections of 3,4-dihydroxyphenylacetaldehyde (DOPAL), a toxic metabolite of dopamine, into the substantia nigra of rats on motor behavior and neuronal survival.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e15251
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pubmed:dateRevised |
2011-7-8
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pubmed:meshHeading |
pubmed-meshheading:21179455-3,4-Dihydroxyphenylacetic Acid,
pubmed-meshheading:21179455-Animals,
pubmed-meshheading:21179455-Behavior, Animal,
pubmed-meshheading:21179455-Dopamine,
pubmed-meshheading:21179455-Glial Fibrillary Acidic Protein,
pubmed-meshheading:21179455-Immunohistochemistry,
pubmed-meshheading:21179455-Male,
pubmed-meshheading:21179455-Microglia,
pubmed-meshheading:21179455-Neurons,
pubmed-meshheading:21179455-Parkinson Disease,
pubmed-meshheading:21179455-Phenotype,
pubmed-meshheading:21179455-Rats,
pubmed-meshheading:21179455-Rats, Sprague-Dawley,
pubmed-meshheading:21179455-Substantia Nigra,
pubmed-meshheading:21179455-Tyrosine 3-Monooxygenase
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pubmed:year |
2010
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pubmed:articleTitle |
The neurotoxicity of DOPAL: behavioral and stereological evidence for its role in Parkinson disease pathogenesis.
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pubmed:affiliation |
Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America. pannetwm@slu.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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