Source:http://linkedlifedata.com/resource/pubmed/id/21178655
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2011-5-18
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pubmed:databankReference | |
pubmed:abstractText |
An open-label study evaluated the safety (n = 53) and pharmacokinetics (n = 8) of single-dose therapy with 1500 mg famciclovir (prodrug of penciclovir) for recurrent herpes labialis in adolescents. Mean Cmax, mean AUC0-?, and clearance for penciclovir were 9.37 ?g/mL, 31.8 ?g · h/mL, and 38.2 L/h, respectively, and within the range extrapolated from data in adults. Adverse events were generally mild and transient.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1532-0987
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
525-8
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pubmed:meshHeading |
pubmed-meshheading:21178655-2-Aminopurine,
pubmed-meshheading:21178655-Adolescent,
pubmed-meshheading:21178655-Antiviral Agents,
pubmed-meshheading:21178655-Child,
pubmed-meshheading:21178655-Female,
pubmed-meshheading:21178655-Herpes Labialis,
pubmed-meshheading:21178655-Humans,
pubmed-meshheading:21178655-Male,
pubmed-meshheading:21178655-Metabolic Clearance Rate,
pubmed-meshheading:21178655-Recurrence,
pubmed-meshheading:21178655-Serum
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pubmed:year |
2011
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pubmed:articleTitle |
Safety and pharmacokinetics of a single 1500-mg dose of famciclovir in adolescents with recurrent herpes labialis.
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pubmed:affiliation |
Department of Pediatrics, University of Kentucky College of Medicine, Louisville, KY, USA. sblock@pol.net
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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