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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-1-31
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pubmed:abstractText |
Haemophilus influenzae type a (Hia) is an important pathogen for some American Indian, Alaskan native, and Northern Canada aboriginal populations. Assays to measure serum bactericidal activity (SBA) to Hia have not been developed or validated. Here, we describe two methods for the measurement of SBA: SBA with a viability endpoint (CFU counts) and SBA with a fluorometric endpoint using alamarBlue as the metabolic indicator. Both SBA assays measure Hia-specific functional antibody and correlate with anti-Hia IgG enzyme-linked immunosorbent assay (ELISA) concentration of naturally acquired antibodies.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-11220764,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-11433097,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-11925021,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-1431250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-14715550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-1538539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-15736015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-15876947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-16267724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-16804859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-17353280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-18258076,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-4120458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-4977280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-6976328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-7814470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21177919-9521143
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1556-679X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
243-7
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pubmed:dateRevised |
2011-8-3
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pubmed:meshHeading |
pubmed-meshheading:21177919-Adult,
pubmed-meshheading:21177919-Bacteriological Techniques,
pubmed-meshheading:21177919-Canada,
pubmed-meshheading:21177919-Colony Count, Microbial,
pubmed-meshheading:21177919-Fluorometry,
pubmed-meshheading:21177919-Haemophilus Infections,
pubmed-meshheading:21177919-Haemophilus influenzae,
pubmed-meshheading:21177919-Humans,
pubmed-meshheading:21177919-Microbial Viability,
pubmed-meshheading:21177919-Middle Aged,
pubmed-meshheading:21177919-Oxazines,
pubmed-meshheading:21177919-Reproducibility of Results,
pubmed-meshheading:21177919-Sensitivity and Specificity,
pubmed-meshheading:21177919-Serum Bactericidal Antibody Assay,
pubmed-meshheading:21177919-Xanthenes
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pubmed:year |
2011
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pubmed:articleTitle |
Evaluation of serum bactericidal antibody assays for Haemophilus influenzae serotype a.
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pubmed:affiliation |
Division of Infectious Diseases, Emory University School of Medicine, 69 Jesse Hill Jr. Drive, Atlanta, Georgia 30303, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Evaluation Studies
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