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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-2-17
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pubmed:abstractText |
Regulatory T cells (Tregs) are thought to inhibit antitumor immune responses, and their depletion could therefore have a synergistic effect with therapeutic cancer vaccines. We investigated the impact of three medications on blood Treg frequency in vaccinated cancer patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cancer Vaccines,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclophosphamide,
http://linkedlifedata.com/resource/pubmed/chemical/Diphtheria Toxin,
http://linkedlifedata.com/resource/pubmed/chemical/FOXP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Forkhead Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Genetic Markers,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/daclizumab,
http://linkedlifedata.com/resource/pubmed/chemical/denileukin diftitox
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AdemaGosse JGJ,
pubmed-author:CastelliChiaraC,
pubmed-author:CouliePierre GPG,
pubmed-author:HuygensCarolineC,
pubmed-author:JacobsJoannes F MJF,
pubmed-author:LucasSophieS,
pubmed-author:PuntCornelis J ACJ,
pubmed-author:RivoltiniLiciaL,
pubmed-author:Schuler-ThurnerBeatriceB,
pubmed-author:SchulerGeroldG,
pubmed-author:StockisJulieJ,
pubmed-author:de VriesI Jolanda MIJ
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pubmed:copyrightInfo |
©2010 AACR.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
841-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21177412-Antibodies, Monoclonal,
pubmed-meshheading:21177412-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:21177412-Antineoplastic Agents,
pubmed-meshheading:21177412-Cancer Vaccines,
pubmed-meshheading:21177412-Cell Count,
pubmed-meshheading:21177412-Cyclophosphamide,
pubmed-meshheading:21177412-DNA Methylation,
pubmed-meshheading:21177412-Diphtheria Toxin,
pubmed-meshheading:21177412-Female,
pubmed-meshheading:21177412-Forkhead Transcription Factors,
pubmed-meshheading:21177412-Genetic Markers,
pubmed-meshheading:21177412-Humans,
pubmed-meshheading:21177412-Immunoglobulin G,
pubmed-meshheading:21177412-Interleukin-2,
pubmed-meshheading:21177412-Introns,
pubmed-meshheading:21177412-Lymphocyte Depletion,
pubmed-meshheading:21177412-Male,
pubmed-meshheading:21177412-Melanoma,
pubmed-meshheading:21177412-Recombinant Fusion Proteins,
pubmed-meshheading:21177412-Retrospective Studies,
pubmed-meshheading:21177412-T-Lymphocytes, Regulatory
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pubmed:year |
2011
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pubmed:articleTitle |
Frequency of circulating Tregs with demethylated FOXP3 intron 1 in melanoma patients receiving tumor vaccines and potentially Treg-depleting agents.
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pubmed:affiliation |
Department of Medical Oncology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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