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pubmed-article:21177407pubmed:abstractTextChemoradiation therapy (CRT) is now widely recognized as bladder-preserving therapy for muscle-invasive bladder cancer (MIBC). However, some patients who fail CRT may miss the chance to be cured by cystectomy. Therefore, it is important to select patients with MIBC who are expected to have a good response to CRT. Several reports indicate that the excision repair cross-complementing group 1 (ERCC1) gene is associated with resistance to cisplatin and radiation therapy. In this study, we examined the correlation between ERCC1 and CRT in vitro and in vivo in bladder cancer.lld:pubmed
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pubmed-article:21177407pubmed:articleTitleExcision repair cross-complementing group 1 may predict the efficacy of chemoradiation therapy for muscle-invasive bladder cancer.lld:pubmed
pubmed-article:21177407pubmed:affiliationThe Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.lld:pubmed
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