Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2011-4-18
pubmed:abstractText
Chemoradiation therapy (CRT) is now widely recognized as bladder-preserving therapy for muscle-invasive bladder cancer (MIBC). However, some patients who fail CRT may miss the chance to be cured by cystectomy. Therefore, it is important to select patients with MIBC who are expected to have a good response to CRT. Several reports indicate that the excision repair cross-complementing group 1 (ERCC1) gene is associated with resistance to cisplatin and radiation therapy. In this study, we examined the correlation between ERCC1 and CRT in vitro and in vivo in bladder cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1078-0432
pubmed:author
pubmed:copyrightInfo
©2010 AACR.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2561-9
pubmed:meshHeading
pubmed-meshheading:21177407-Aged, pubmed-meshheading:21177407-Aged, 80 and over, pubmed-meshheading:21177407-Antineoplastic Agents, pubmed-meshheading:21177407-Blotting, Western, pubmed-meshheading:21177407-Cell Line, Tumor, pubmed-meshheading:21177407-Cell Survival, pubmed-meshheading:21177407-Cisplatin, pubmed-meshheading:21177407-Combined Modality Therapy, pubmed-meshheading:21177407-DNA-Binding Proteins, pubmed-meshheading:21177407-Endonucleases, pubmed-meshheading:21177407-Female, pubmed-meshheading:21177407-Gene Expression Regulation, Neoplastic, pubmed-meshheading:21177407-Humans, pubmed-meshheading:21177407-Immunohistochemistry, pubmed-meshheading:21177407-Male, pubmed-meshheading:21177407-Middle Aged, pubmed-meshheading:21177407-Muscles, pubmed-meshheading:21177407-Neoplasm Invasiveness, pubmed-meshheading:21177407-Prognosis, pubmed-meshheading:21177407-RNA Interference, pubmed-meshheading:21177407-Radiotherapy, pubmed-meshheading:21177407-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:21177407-Treatment Outcome, pubmed-meshheading:21177407-Urinary Bladder Neoplasms
pubmed:year
2011
pubmed:articleTitle
Excision repair cross-complementing group 1 may predict the efficacy of chemoradiation therapy for muscle-invasive bladder cancer.
pubmed:affiliation
The Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
pubmed:publicationType
Journal Article