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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2011-3-7
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pubmed:abstractText |
Adipocyte fatty acid-binding protein (A-FABP) is up-regulated in regenerated endothelial cells and modulates inflammatory responses in macrophages. Endothelial dysfunction accompanying regeneration is accelerated by hyperlipidaemia. Here, we investigate the contribution of A-FABP to the pathogenesis of endothelial dysfunction in the aorta of apolipoprotein E-deficient (ApoE(-/-) ) mice and in cultured human endothelial cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-(2'-(5-ethyl-3,4-diphenyl-1H-pyraz...,
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic alpha-2 Receptor Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/Biphenyl Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Calcimycin,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acid-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1476-5381
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pubmed:author |
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pubmed:copyrightInfo |
© 2011 The Authors. British Journal of Pharmacology © 2011 The British Pharmacological Society.
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pubmed:issnType |
Electronic
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pubmed:volume |
162
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1564-76
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21175571-Acetylcholine,
pubmed-meshheading:21175571-Adipocytes,
pubmed-meshheading:21175571-Adrenergic alpha-2 Receptor Agonists,
pubmed-meshheading:21175571-Animals,
pubmed-meshheading:21175571-Aorta,
pubmed-meshheading:21175571-Apolipoproteins E,
pubmed-meshheading:21175571-Biphenyl Compounds,
pubmed-meshheading:21175571-Blood Glucose,
pubmed-meshheading:21175571-Calcimycin,
pubmed-meshheading:21175571-Cells, Cultured,
pubmed-meshheading:21175571-Endothelial Cells,
pubmed-meshheading:21175571-Endothelium, Vascular,
pubmed-meshheading:21175571-Fatty Acid-Binding Proteins,
pubmed-meshheading:21175571-Female,
pubmed-meshheading:21175571-Humans,
pubmed-meshheading:21175571-Insulin,
pubmed-meshheading:21175571-Lipids,
pubmed-meshheading:21175571-Male,
pubmed-meshheading:21175571-Mice,
pubmed-meshheading:21175571-Mice, Inbred C57BL,
pubmed-meshheading:21175571-Mice, Knockout,
pubmed-meshheading:21175571-Nitric Oxide,
pubmed-meshheading:21175571-Nitric Oxide Synthase Type III,
pubmed-meshheading:21175571-Pyrazoles,
pubmed-meshheading:21175571-Vasodilation
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pubmed:year |
2011
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pubmed:articleTitle |
Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.
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pubmed:affiliation |
Department of Pharmacology & Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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