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pubmed-article:21175304pubmed:abstractTextAmplification and activating mutations of the epidermal growth factor receptor (EGFR) oncogene are molecular hallmarks of glioblastomas. We hypothesized that deletion of NFKBIA (encoding nuclear factor of ?-light polypeptide gene enhancer in B-cells inhibitor-?), an inhibitor of the EGFR-signaling pathway, promotes tumorigenesis in glioblastomas that do not have alterations of EGFR.lld:pubmed
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pubmed-article:21175304pubmed:affiliationDepartment of Neurosurgery, Neurocenter, University of Freiburg, Freiburg, Germany. markus.bredel@uniklinik-freiburg.delld:pubmed
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