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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2011-1-10
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pubmed:abstractText |
Adenoid cystic carcinoma is one of the most common types of salivary gland cancers. The poor long-term prognosis for patients with adenoid cystic carcinoma is mainly due to local recurrence and distant metastasis. Disintegrin and metalloprotease 10 (ADAM 10) is a transmembrane protein associated with metastasis in a number of diverse of cancers. The aim of this study was to analyze the relationship between ADAM 10 and the invasive and metastatic potentials as well as the proliferation capability of adenoid cystic carcinoma cells in vitro and in vivo.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1479-5876
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
136
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pubmed:dateRevised |
2011-7-20
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pubmed:meshHeading |
pubmed-meshheading:21171968-ADAM Proteins,
pubmed-meshheading:21171968-Amyloid Precursor Protein Secretases,
pubmed-meshheading:21171968-Animals,
pubmed-meshheading:21171968-Carcinoma, Adenoid Cystic,
pubmed-meshheading:21171968-Cell Line, Tumor,
pubmed-meshheading:21171968-Cell Movement,
pubmed-meshheading:21171968-Cell Proliferation,
pubmed-meshheading:21171968-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21171968-Gene Silencing,
pubmed-meshheading:21171968-Humans,
pubmed-meshheading:21171968-Immunohistochemistry,
pubmed-meshheading:21171968-Membrane Proteins,
pubmed-meshheading:21171968-Mice,
pubmed-meshheading:21171968-Neoplasm Metastasis,
pubmed-meshheading:21171968-RNA, Messenger,
pubmed-meshheading:21171968-RNA Interference
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pubmed:year |
2010
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pubmed:articleTitle |
Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference.
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pubmed:affiliation |
Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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