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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-20
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pubmed:abstractText |
Lung cancer is the leading cause of cancer deaths worldwide. New diagnostics are needed to detect early stage lung cancer because it may be cured with surgery. However, most cases are diagnosed too late for curative surgery. Here we present a comprehensive clinical biomarker study of lung cancer and the first large-scale clinical application of a new aptamer-based proteomic technology to discover blood protein biomarkers in disease.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:BigbeeWilliam LWL,
pubmed-author:BrodyEdward NEN,
pubmed-author:FranklinWilburW,
pubmed-author:GoldLarryL,
pubmed-author:MehanMikeM,
pubmed-author:MillerYork EYE,
pubmed-author:OstroffRachel MRM,
pubmed-author:PassHarvey IHI,
pubmed-author:RomWilliam NWN,
pubmed-author:SiegfriedJill MJM,
pubmed-author:StewartAlexA,
pubmed-author:WalkerJeffrey JJJ,
pubmed-author:WeissfeldJoel LJL,
pubmed-author:WilliamsStephenS,
pubmed-author:ZichiDomD
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e15003
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:21170350-Algorithms,
pubmed-meshheading:21170350-Autoantibodies,
pubmed-meshheading:21170350-Biological Markers,
pubmed-meshheading:21170350-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:21170350-Case-Control Studies,
pubmed-meshheading:21170350-Cohort Studies,
pubmed-meshheading:21170350-Early Detection of Cancer,
pubmed-meshheading:21170350-Humans,
pubmed-meshheading:21170350-Lung Neoplasms,
pubmed-meshheading:21170350-Mass Spectrometry,
pubmed-meshheading:21170350-Models, Statistical,
pubmed-meshheading:21170350-Proteomics,
pubmed-meshheading:21170350-Sensitivity and Specificity,
pubmed-meshheading:21170350-Smoking,
pubmed-meshheading:21170350-Tumor Markers, Biological
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pubmed:year |
2010
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pubmed:articleTitle |
Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer.
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pubmed:affiliation |
SomaLogic, Boulder, Colorado, United States of America. rostroff@somalogic.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Research Support, N.I.H., Extramural
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