Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-4-7
pubmed:databankReference
pubmed:abstractText
Intervention for cystic fibrosis lung disease early in its course has the potential to delay or prevent progressive changes that lead to irreversible airflow obstruction. Denufosol is a novel ion channel regulator designed to correct the ion transport defect and increase the overall mucociliary clearance in cystic fibrosis lung disease by increasing chloride secretion, inhibiting sodium absorption, and increasing ciliary beat frequency in the airway epithelium independently of cystic fibrosis transmembrane conductance regulator genotype.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1535-4970
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
183
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
627-34
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Denufosol tetrasodium in patients with cystic fibrosis and normal to mildly impaired lung function.
pubmed:affiliation
University of Colorado Denver, 13123 East 16th Avenue, B395, Aurora, CO 80045. accurso.frank@tchden.org.
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Clinical Trial, Phase III